Role of Porphyromonas gingivalis gingipains in multi-species biofilm formation

Porphyromonas gingivalis Formation by Role of Polyphosphate Kinase in Biofilm

Involvement of respiratory chain in biofilm formation in porphyromonas gingivalis.

Introduction Porphyromonas gingivalis (P.gingivalis) is a gram-negative strict-anaerobe bacterium and constitutes one of the main pathogen responsible for periodontal diseases (2). Periodontal diseases are chronic inflammatory infections induced by bacteria organised in biofilm. More than 500 bacteria species take part in this biofilm including P. gingivalis (3). Although strict-anaerobe, P. gi...

Stimulation of Fusobacterium nucleatum biofilm formation by Porphyromonas gingivalis.

BACKGROUND/AIMS Bacterial infection is a major cause of periapical periodontitis. Eradication of these microorganisms from apical lesions is essential to the success of endodontic treatment. The aim of this study was to clarify the molecular interaction between Fusobacterium nucleatum, Porphyromonas gingivalis and other microorganisms associated with periapical periodontitis. METHODS Microorg...

Role of gingipains in growth of Porphyromonas gingivalis in the presence of human serum albumin.

Porphyromonas gingivalis, a bacterium associated with active chronic periodontitis lesions, produces several proteolytic enzymes that are thought to be involved in host colonization, perturbation of the immune system, and tissue destruction. The aim of the present study was to investigate the contribution of Arg- and Lys-gingipains produced by P. gingivalis to its growth. Although all of the pr...

Tobacco Smoke Augments Porphyromonas gingivalis - Streptococcus gordonii Biofilm Formation

Smoking is responsible for the majority of periodontitis cases in the US and smokers are more susceptible than non-smokers to infection by the periodontal pathogen Porphyromonas gingivalis. P. gingivalis colonization of the oral cavity is dependent upon its interaction with other plaque bacteria, including Streptococcus gordonii. Microarray analysis suggested that exposure of P. gingivalis to c...